Research Outputs

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http://hdl.handle.net/20.500.11837/3255

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Browsing Research Outputs by Author "Okoh, Anthony Ifeanyi"

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    Draft genome sequence of multi-drug resistant Klebsiella quasipneumoniae subsp. similipneumoniae isolated from a teaching hospital wastewater in South West, Nigeria.
    (American Society for Microbiology, 2024-01-24) Akinola, Omowumi T.; Dahunsi, Samuel O.; Okoh, Anthony Ifeanyi
    This broadcast is about the whole genome sequence of Klebsiella quasipneumoniae subsp. similipneumoniae (ST 1422) isolated from a teaching hospital wastewater in South West, Nigeria, in May 2022. This data set compiles information on the DNA size (5,332,183 bp) and GC content (57.91%) in its genome.
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    Virulence Signatures, Integrons, and Antibiotic Resistance Genes in Bacterial Strains Recovered from Selected Commercial Dairy Products and Fresh Raw Meat
    (Springer, 2023-06-24) Aiyegoro, Olayinka A.; Moyane, Jeremia N.; Adegoke, Anthony A.; Jideani, Afam I.O.; Reddy, Poovendhree; Okoh, Anthony Ifeanyi
    Bacterial species responsible for food infections and intoxication are sometimes carried through the food production and processing. Very few published literatures exist on integrons among antibiotic-resistant staphylococcal strains from foods of animal origin in Gauteng Province, South Africa, hence this study. A total of 720 samples (360 meat and 360 dairies) from a community abattoir of a research farm in South Africa, using conventional bacteriological and molecular methods. Nine (9) bacterial strains, including Bacillus subtilis AYO-123, Acinetobacter baumannii AYO-241, Staphylococcus lentus AYO-352, among others were identified and submitted to GenBank. More bacterial strains were recovered from raw meat (90.5%) than dairy products (9.5%). Resistance was shown (0–100%) to Imipenem, Meropenem, Norfloxacin, Clindamycin, and 22 other antibiotics, without any carbapenem-resistant Acinetobacter baumannii and methicillin/vancomycin-resistant Staphylococcus species (MRSS/VRSS). Virulence genes for fibronectin-binding protein A (FnbA) were predominant (56.24%) followed by the circulating nucleic acids (cna) gene (43.75%). Others were staphylococcal enterotoxin A (sea, 41%), staphylococcal enterotoxin B (seb, 23.5%). Co-presence of sea and seb genes occurred in 11.76% of the isolates, but no coa genes was amplified. Antibiotic resistance genes (ARGs), tetK (70.58%), linA (29.4%), and ermA (11.76%) were detected, but none of the mecA and vat genes was amplified. Class 2 integron (50%) was more predominantly detected than integron 1 (25%), but no Class 3 integron was detected. Bacteria with both the detected virulence and antibiotic resistance genes are of potentialrisks to human health.