Electrospun Nanofibers/Nanofibrous Scaffolds Loaded with Silver Nanoparticles as Effective Antibacterial Wound Dressing Materials
| dc.contributor.author | Alven, Sibusiso | |
| dc.contributor.author | Buyana, Buhle 0000-0002-2895-1815 | |
| dc.contributor.author | Feketshane, Zizo 0000-0002-2671-7566 | |
| dc.contributor.author | Aderibigbe, Blessing Atim 0000-0003-1157-7481 | |
| dc.date.accessioned | 2026-02-22T08:05:07Z | |
| dc.date.available | 2026-02-22T08:05:07Z | |
| dc.date.issued | 2021-06-26 | |
| dc.description.abstract | The treatment of wounds is expensive and challenging. Most of the available wound dressings are not effective and suffer from limitations such as poor antimicrobial activity, toxicity, inability to provide suitable moisture to the wound and poor mechanical performance. The use of inappropriate wound dressings can result in a delayed wound healing process. Nanosize range scaffolds have triggered great attention because of their attractive properties, which include their capability to deliver bioactive agents, high surface area, improved mechanical properties, mimic the extracellular matrix (ECM), and high porosity. Nanofibrous materials can be further encapsulated/loaded with metal-based nanoparticles to enhance their therapeutic outcomes in wound healing applications. The widely studied metal-based nanoparticles, silver nanoparticles exhibit good properties such as outstanding antibacterial activity, display antioxidant, and anti-inflammatory properties, support cell growth, making it an essential bioactive agent in wound dressings. This review article reports the biological (in vivo and in vitro) and mechanical outcomes of nanofibrous scaffolds loaded with silver nanoparticles on wound healing | |
| dc.description.sponsorship | The financial assistance of the Govan Mbeki Research and Development Centre, University of Fort Hare, Medical Research Council and National Research Foundation, South Africa towards this research are hereby acknowledged. The views and opinions expressed in this manuscript are those of the authors and not of MRC or NRF. | |
| dc.identifier.citation | Alven, S.; Buyana, B.; Feketshane, Z.; Aderibigbe, B.A. Electrospun Nanofibers/Nanofibrous Scaffolds Loaded with Silver Nanoparticles as Effective Antibacterial Wound Dressing Materials. Pharmaceutics 2021, 13, 964. https://doi.org/10.3390/ pharmaceutics13070964 | |
| dc.identifier.issn | 1999-4923 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11837/3799 | |
| dc.language.iso | en | |
| dc.publisher | MDPI | |
| dc.subject | wound treatment | |
| dc.subject | wound dressings | |
| dc.subject | scaffolds | |
| dc.subject | nanofibers | |
| dc.subject | nanofibrous membranes | |
| dc.subject | nanofibrous mats | |
| dc.subject | and nanoparticles | |
| dc.title | Electrospun Nanofibers/Nanofibrous Scaffolds Loaded with Silver Nanoparticles as Effective Antibacterial Wound Dressing Materials | |
| dc.type | Article |