Fabrication of Hybrid Nanofibers from Biopolymers and Poly (Vinyl Alcohol)/Poly (ε-Caprolactone) for Wound Dressing Applications
| dc.contributor.author | Alven, S | |
| dc.contributor.author | Aderibigbe, Blessing A 0000-0003-1157-7481 | |
| dc.date.accessioned | 2026-02-22T07:20:33Z | |
| dc.date.available | 2026-02-22T07:20:33Z | |
| dc.date.issued | 2021-06-26 | |
| dc.description.abstract | The management of chronic wounds is challenging. The factors that impede wound healing include malnutrition, diseases (such as diabetes, cancer), and bacterial infection. Most of the presently utilized wound dressing materials suffer from severe limitations, including poor antibacterial and mechanical properties. Wound dressings formulated from the combination of biopolymers and synthetic polymers (i.e., poly (vinyl alcohol) or poly (ε-caprolactone) display interesting properties, including good biocompatibility, improved biodegradation, good mechanical properties and antimicrobial effects, promote tissue regeneration, etc. Formulation of these wound dressings via electrospinning technique is cost-effective, useful for uniform and continuous nanofibers with controllable pore structure, high porosity, excellent swelling capacity, good gaseous exchange, excellent cellular adhesion, and show a good capability to provide moisture and warmth environment for the accelerated wound healing process. Based on the above-mentioned outstanding properties of nanofibers and the unique properties of hybrid wound dressings prepared from poly (vinyl alcohol) and poly (ε-caprolactone), this review reports the in vitro and in vivo outcomes of the reported hybrid nanofibers. | |
| dc.description.sponsorship | The financial assistance of the Govan Mbeki Research and Development Council, University of Fort Hare, Medical Research Council, and National Research Foundation, South Africa, towards Polymers 2021, 13, 2104 26 of 32 this research are hereby acknowledged. The views and opinions expressed in this manuscript are those of the authors and not of MRC or NRF | |
| dc.identifier.citation | Alven, S.; Aderibigbe, B.A. Fabrication of Hybrid Nanofibers from Biopolymers and Poly (Vinyl Alcohol)/Poly (ε-Caprolactone) for Wound Dressing Applications. Polymers 2021, 13, 2104. https:// doi.org/10.3390/polym13132104 | |
| dc.identifier.issn | 2073-4360 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11837/3797 | |
| dc.language.iso | en | |
| dc.publisher | MDPI | |
| dc.subject | wound dressing | |
| dc.subject | biopolymers | |
| dc.subject | poly (vinyl alcohol) | |
| dc.subject | poly (ε-caprolactone) | |
| dc.subject | electrospinning | |
| dc.subject | nanofibers | |
| dc.title | Fabrication of Hybrid Nanofibers from Biopolymers and Poly (Vinyl Alcohol)/Poly (ε-Caprolactone) for Wound Dressing Applications | |
| dc.type | Article |